MIM1

MIM1 is an inhibitor of Mcl-1, an antiapoptotic Bcl-2 family protein that selectively engages the canonical groove of Mcl-1, inhibiting its ability to bind BH3 domains. MIM1 induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells.

Product information

CAS Number: 509102-00-5

Molecular Weight: 347.43

Formula: C17H21N3O3S

Synonym:

MIM 1

MIM-1

Inhibitor of Mcl-1

Chemical Name: 4-[(1E)-{[2-(cyclohexylimino)-4-methyl-2,3-dihydro-1,3-thiazol-3-yl]imino}methyl]benzene-1,2,3-triol

Smiles: CC1=CSC(=NC2CCCCC2)N1/N=C/C1=CC=C(O)C(O)=C1O

InChiKey: RGGFUBMUOVFZEF-LDRVEFRDSA-N

InChi: InChI=1S/C17H21N3O3S/c1-11-10-24-17(19-13-5-3-2-4-6-13)20(11)18-9-12-7-8-14(21)16(23)15(12)22/h7-10,13,21-23H,2-6H2,1H3/b18-9+,19-17-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.