Description
NP-118809 is a N-type calcium channel blocker. NP-118809 exhibits both anti-allodynic and anti-hyperalgesic activity in the spinal nerve ligation model of neuropathic pain. NP118809 further exhibits a number of favorable preclinical characteristics as they relate to overall pharmacokinetics and minimal off-target activity including the hERG potassium channel.
Product information
CAS Number: 41332-24-5
Molecular Weight: 460.61
Formula: C32H32N2O
Chemical Name: 1-[4-(diphenylmethyl)piperazin-1-yl]-3,3-diphenylpropan-1-one
Smiles: O=C(CC(C1C=CC=CC=1)C1C=CC=CC=1)N1CCN(CC1)C(C1C=CC=CC=1)C1C=CC=CC=1
InChiKey: VCPMZDWBEWTGNW-UHFFFAOYSA-N
InChi: InChI=1S/C32H32N2O/c35-31(25-30(26-13-5-1-6-14-26)27-15-7-2-8-16-27)33-21-23-34(24-22-33)32(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20,30,32H,21-25H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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