BS-181


Catalog No. Size PriceQuantity
M11153-2 Solid 2 mg $90
M11153-10 Solid 10 mg $270

Description

Normal progression through the cell cycle requires the sequential action of cyclin-dependent kinases (CDK1, CDK2, CDK4 and CDK6). Deregulation of CDK activity is a feature of almost all cancers and has led to the development of CDK inhibitors as anticancer agents. As such, CDK7 is an target for the anticancer drug development. Computer modeling of CDK7 was used to design potential potent CDK7 inhibitor, which is BS-181.

Product information

CAS Number: 1092443-52-1

Molecular Weight: 380.53

Formula: C22H32N6

Chemical Name: N5-(6-aminohexyl)-N7-benzyl-3-(propan-2-yl)pyrazolo[1,5-a]pyrimidine-5,7-diamine

Smiles: CC(C)C1C=NN2C(=CC(NCCCCCCN)=NC2=1)NCC1C=CC=CC=1

InChiKey: DNYBIOICMDTDAP-UHFFFAOYSA-N

InChi: InChI=1S/C22H32N6/c1-17(2)19-16-26-28-21(25-15-18-10-6-5-7-11-18)14-20(27-22(19)28)24-13-9-4-3-8-12-23/h5-7,10-11,14,16-17,25H,3-4,8-9,12-13,15,23H2,1-2H3,(H,24,27)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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