Quetiapine sulfoxide hydrochloride - CAS# 2448341-72-6


Catalog No. Size PriceQuantity
M17458-C Contact sales@xcessbio.com for quotation $100

Description

Quetiapine sulfoxide hydrochloride (Quetiapine S-oxide hydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist.

Product information

CAS Number: 2448341-72-6

Molecular Weight: 435.97

Formula: C21H26ClN3O3S

Chemical Name: 10-{4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl}-2λ⁴-thia-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3,5,7,9,12,14-heptaen-2-one hydrochloride

Smiles: Cl.OCCOCCN1CCN(CC1)C1=NC2=CC=CC=C2S(=O)C2C=CC=CC1=2

InChiKey: BJOYEAHGKKTINJ-UHFFFAOYSA-N

InChi: InChI=1S/C21H25N3O3S.ClH/c25-14-16-27-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)28(26)20-8-4-2-6-18(20)22-21;/h1-8,25H,9-16H2;1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

The Cmax value (mean±SD) is estimated for Quetiapine sulfoxide (77.3±32.4 ng/mL). The AUClast value is estimated for Quetiapine sulfoxide (1,286±458 ng•h/mL). For Quetiapine sulfoxide, metabolic ratio decreases with time, from 119% on average 2 hours after dosing to 30% on average 72 hours after dosing.

Products are for research use only. Not for human use.

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