Description
Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes.
Product information
CAS Number: 107-35-7
Molecular Weight: 125.15
Formula: C2H7NO3S
Synonym:
β-Aminoethylsulfonic Acid
NSC 32428
Chemical Name: 2-aminoethane-1-sulfonic acid
Smiles: NCCS(O)(=O)=O
InChiKey: XOAAWQZATWQOTB-UHFFFAOYSA-N
InChi: InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: Insoluble. Water: 20 mg/mL(159.8 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Taurine is present in high concentration in algae and in the animals including insects and arthropods, but is generally absent or present in traces in the bacterial and plant kingdoms. In cardiac tissue alone, taurine levels of 20 mM or higher may be found. Taurine availability protects against cholestasis induced by monohydroxy bile acids remains confined to guinea pigs. In addition, Taurine is an essential nutrient for the cat. Oral supplementation of taurine results in increased plasma taurine concentrations and is associated with normalization of left ventricular function in both groups of cats. Myocardial concentrations of taurine are directly related to plasma concentrations and low plasma concentrations are found to be associated with myocardial failure in cats, proposing a direct link occurs between decreased taurine concentration in the myocardium and decreased myocardial mechanical function.
References:
- Knopf K, et al. J Nutr, 1978, 108(5), 773-778.
- Chesney RW. Adv Pediatr, 1985, 32, 1-42.
- Huxtable RJ. Prog Neurobiol, 1989, 32(6), 471-533.
Products are for research use only. Not for human use.
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