PROTAC CBP/P300 Degrader-1


Catalog No. Size PriceQuantity
M33901-C Contact sales@xcessbio.com for quotation $100

Description

PROTAC CBP/P300 Degrader-1 is a potent PROTAC CBP/P300 degrader. PROTAC CBP/P300 Degrader-1 potently inhibited cell viability of multiple cancer cell lines.

Product information

CAS Number: 2484739-48-0

Molecular Weight: 893.98

Formula: C46H53F2N11O6

Smiles: CN1C=C(C=N1)C1=CC2CCCN(C3=NN(C4CCN(CC4)C(=O)CCCCCNC4=CC=CC5C(=O)N(C6CCC(=O)NC6=O)C(=O)C=54)C4CCN(CC=43)C(=O)NC)C=2C=C1C(F)F

InChiKey: KOXRGDZBEAJAKE-UHFFFAOYSA-N

InChi: InChI=1S/C46H53F2N11O6/c1-49-46(65)56-21-16-35-33(26-56)42(57-18-7-8-27-22-31(28-24-51-54(2)25-28)32(41(47)48)23-37(27)57)53-59(35)29-14-19-55(20-15-29)39(61)11-4-3-5-17-50-34-10-6-9-30-40(34)45(64)58(44(30)63)36-12-13-38(60)52-43(36)62/h6,9-10,22-25,29,36,41,50H,3-5,7-8,11-21,26H2,1-2H3,(H,49,65)(H,52,60,62)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Jing Liu, et al. Cyclic-amp response element binding protein (cbp) and/or adenoviral e1a binding protein of 300 kda (p300) degradation compounds and methods of use. WO2020173440A1.

Products are for research use only. Not for human use.

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