Description
Glucocorticoid receptor agonist, CAS No. 1245526-82-2, is a potent Glucocorticoid receptor agonist. Glucocorticoid receptor agonist acts on Glucocorticoid receptor (GR), progesterone receptor (PR) and mineralocorticoid receptor (MR) with the IC50 values of 2.1 , 1200 and 210 nM, respectively. Glucocorticoid receptor agonist has steroid-like anti-inflammatory properties and may be used to improve metabolism and reduce increased levels of body fat and serum insulin.
Product information
CAS Number: 1245526-82-2
Molecular Weight: 396.38
Formula: C20H20F4N2O2
Synonym:
1H-Pyrrolo[2,3-c]pyridine-2-ethanol, α-[2-(5-fluoro-2-hydroxyphenyl)-2-methylpropyl]-α-(trifluoromethyl)-, (αR)-
Chemical Name: 4-fluoro-2-[(4R)-5,5,5-trifluoro-4-hydroxy-2-methyl-4-({1H-pyrrolo[2,3-c]pyridin-2-yl}methyl)pentan-2-yl]phenol
Smiles: CC(C)(C[C@@](O)(CC1=CC2=CC=NC=C2N1)C(F)(F)F)C1=CC(F)=CC=C1O
InChiKey: JFUAWXPBHXKZGA-IBGZPJMESA-N
InChi: InChI=1S/C20H20F4N2O2/c1-18(2,15-8-13(21)3-4-17(15)27)11-19(28,20(22,23)24)9-14-7-12-5-6-25-10-16(12)26-14/h3-8,10,26-28H,9,11H2,1-2H3/t19-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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