MPO-IN-28

MPO-IN-28 (Compound 28) is an inhibitor of myeloperoxidase (MPO) with IC50 of 44 nM.

Product information

CAS Number: 37836-90-1

Molecular Weight: 231.25

Formula: C11H13N5O

Chemical Name: 2-(7-Methoxy-4-methyl-2-quinazolinyl)guanidine

Smiles: CC1=NC(N=C(N)N)=NC2=CC(=CC=C12)OC

InChiKey: ZJBMSSBTCGJZEE-UHFFFAOYSA-N

InChi: InChI=1S/C11H13N5O/c1-6-8-4-3-7(17-2)5-9(8)15-11(14-6)16-10(12)13/h3-5H,1-2H3,(H4,12,13,14,15,16)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 46 mg/mL (198.92 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Jalal Soubhye, et al. J Med Chem. 2017 Aug 10;60(15):6563-65

Products are for research use only. Not for human use.