Bavisant (dihydrochloride hydrate)


Catalog No. Size PriceQuantity
M9633-2 Solid 2 mg $110
M9633-10 Solid 10 mg $330

Description

Bavisant, also known as JNJ-31001074, is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. Histamine H3 receptors reside on non-histamine neurons and regulate other neurotransmitters (e.g. acetylcholine, noradrenaline [norepinephrine]) suggesting that H3 antagonists have the potential to improve attention and impulsivity. Research indicates that H3 receptor antagonists due to their novel mechanism of action may have a unique treatment effect offering an important alternative for the treatment of ADHD.

Product information

CAS Number: 1103522-80-0

Molecular Weight: 420.37

Formula: C19H31Cl2N3O3

Chemical Name: 4-{[4-(4-cyclopropylpiperazine-1-carbonyl)phenyl]methyl}morpholine hydrate dihydrochloride

Smiles: O.Cl.Cl.O=C(C1C=CC(CN2CCOCC2)=CC=1)N1CCN(CC1)C1CC1

InChiKey: BLFBQJUVAGIUBL-UHFFFAOYSA-N

InChi: InChI=1S/C19H27N3O2.2ClH.H2O/c23-19(22-9-7-21(8-10-22)18-5-6-18)17-3-1-16(2-4-17)15-20-11-13-24-14-12-20;;;/h1-4,18H,5-15H2;2*1H;1H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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