Oleanolic Acid

Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.

Product information

CAS Number: 508-02-1

Molecular Weight: 456.70

Formula: C30H48O3

Synonym:

Oleanic acid

Caryophyllin

Related CAS Number:

1975976-24-9 (Oleanolic acid acrylate)

Chemical Name: (4aS, 6aS, 6bR, 8aR, 10S, 12aR, 12bR, 14bS)-10-hydroxy-2, 2, 6a, 6b, 9, 9, 12a-heptamethyl-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 12b, 13, 14b-icosahydropicene-4a-carboxylic acid

Smiles: CC1(C)C[C@H]2C3=CC[C@H]4[C@@](C)(CC[C@@H]5[C@]4(C)CC[C@H](O)C5(C)C)[C@]3(C)CC[C@]2(CC1)C(O)=O

InChiKey: MIJYXULNPSFWEK-GTOFXWBISA-N

InChi: InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,23-,27-,28+,29+,30-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 21 mg/mL(45.98 mM). Water: Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Oleanolic Acid is a non-toxic, hepatoprotective triterpenoid found in Phytolacca Americana which exerts antitumor and antiviral properties. Oleanolic acid is effective in protecting against chemically induced liver injury in laboratory animals. Oleanolic acid are relatively non-toxic, and has been used in cosmetics and health products. Oleanolic acid was found to exhibit weak anti-HIV and weak anti-HCV activities, but more potent synthetic analogs are being investigated as potential drugs.

References:

1. Mengoni F, Planta Med, 2002, 68(2), 111-114.
2. Liu J, J Ethnopharmacol, 1995, 49(2), 57-68.

Products are for research use only. Not for human use.