Description
BAY65-1942 is an ATP-competitive inhibitor that selectively targets IKKbeta kinase activity. IKKbeta inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury.
Product information
CAS Number: 600734-02-9
Molecular Weight: 395.45
Formula: C22H25N3O4
Chemical Name: 7-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-5-[(3S)-piperidin-3-yl]-1H,2H,4H-pyrido[2,3-d][1,3]oxazin-2-one
Smiles: OC1=CC=CC(OCC2CC2)=C1C1=CC([C@H]2CNCCC2)=C2COC(=O)NC2=N1
InChiKey: IGJVFGZEWDGDOO-CQSZACIVSA-N
InChi: InChI=1S/C22H25N3O4/c26-18-4-1-5-19(28-11-13-6-7-13)20(18)17-9-15(14-3-2-8-23-10-14)16-12-29-22(27)25-21(16)24-17/h1,4-5,9,13-14,23,26H,2-3,6-8,10-12H2,(H,24,25,27)/t14-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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