Bestatin-amido-Me


Catalog No. Size PriceQuantity
M11572-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bestatin-amido-Me, the Bestatin-based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER.

Product information

CAS Number: 339186-54-8

Molecular Weight: 321.41

Formula: C17H27N3O3

Synonym:

PROTAC IAP binding moiety 1

Chemical Name: (2S)-2-[(2S, 3R)-3-amino-2-hydroxy-4-phenylbutanamido]-N, 4-dimethylpentanamide

Smiles: CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1C=CC=CC=1)C(=O)NC

InChiKey: WXXGFNCJBKSHFH-ILXRZTDVSA-N

InChi: InChI=1S/C17H27N3O3/c1-11(2)9-14(16(22)19-3)20-17(23)15(21)13(18)10-12-7-5-4-6-8-12/h4-8,11,13-15,21H,9-10,18H2,1-3H3,(H,19,22)(H,20,23)/t13-,14+,15+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Products are for research use only. Not for human use.

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