Description
Malotilate is a hepatoprotective agent that inhibits A23187-induced metabolism of arachidonic acid to the 5-lipoxygenase (5-LO) metabolites leukotriene B4 (LTB4) and 5-HETE. Malotilate prevents increases in plasma glutamic-pyruvic transaminase (GPT) and glutamic-oxaloacetic transaminase (GOT) activities in a rat model of carbon tetrachloride-induced liver injury. It reduces hepatic deposition of type III procollagen, type IV collagen, laminin, and fibronectin in a rat model of dimethylnitrosamine-induced hepatic fibrosis.
Product information
CAS Number: 59937-28-9
Molecular Weight: 288.38
Formula: C12H16O4S2
Chemical Name: 1,3-bis(propan-2-yl) 2-(2H-1,3-dithiol-2-ylidene)propanedioate
Smiles: CC(C)OC(=O)C(=C1SC=CS1)C(=O)OC(C)C
InChiKey: YPIQVCUJEKAZCP-UHFFFAOYSA-N
InChi: InChI=1S/C12H16O4S2/c1-7(2)15-10(13)9(11(14)16-8(3)4)12-17-5-6-18-12/h5-8H,1-4H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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