D-glutamine

D-Glutamine is a cell-permeable D type stereoisomer of Glutamine.

Product information

CAS Number: 5959-95-5

Molecular Weight: 146.14

Formula: C5H10N2O3

Chemical Name: (2R)-2-amino-4-carbamoylbutanoic acid

Smiles: NC(=O)CC[C@@H](N)C(O)=O

InChiKey: ZDXPYRJPNDTMRX-GSVOUGTGSA-N

InChi: InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: Insoluble. Water: 9 mg/mL(61.58 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

In catabolic states of injury and illness, glutamine becomes conditionally-essential (requiring intake from food or supplements). Glutamine is the most abundant naturally occurring, non-essential amino acid in the human body and one of the few amino acids that can directly cross the blood–brain barrier. Glutamine is a key pharmaconutrient in the body's response to stress and injury. Glutamine exerts its protective effects via multiple mechanisms, including direct protection of cells and tissue from injury, attenuation inflammation, and preservation of metabolic function.

In Vivo:

Glutamine shows the greatest benefit when administered at doses greater than 0.35 g/kg/day, with optimal benefit potentially occurring at 0.5 g/kg/day

References:

1. Kim M, et al. World Rev Nutr Diet, 2013, 105, 90-96.
2. Lee WJ, et al. Am J Physiol, 1998, 274(4 Pt 1), C1101-C1107.

Products are for research use only. Not for human use.