7ACC2


Catalog No. size PriceQuantity
M6603-2 2mg solid $113
M6603-10 10mg solid $436

Description

7ACC2 is a potent MCT inhibitor. Monocarboxylate transporters (MCTs) catalyze the proton-linked transport of monocarboxylates such as L-lactate, pyruvate, and the ketone bodies across the plasma membrane. There are four isoforms, MCTs 1-4, which are known to perform this function in mammals, each with distinct substrate and inhibitor affinities.

Product information

CAS Number: 1472624-85-3

Molecular Weight: 309.32

Formula: C18H15NO4

Synonym:

7-ACC2

7ACC2

7 ACC2

Chemical Name: 7-(benzyl(methyl)amino)-2-oxo-2H-chromene-3-carboxylic acid

Smiles: CN(CC1C=CC=CC=1)C1=CC2OC(=O)C(=CC=2C=C1)C(O)=O

InChiKey: XTKDQPFUOFAMRL-UHFFFAOYSA-N

InChi: InChI=1S/C18H15NO4/c1-19(11-12-5-3-2-4-6-12)14-8-7-13-9-15(17(20)21)18(22)23-16(13)10-14/h2-10H,11H2,1H3,(H,20,21)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

  1. Draoui N, et al. Synthesis and pharmacological evaluation of carboxycoumarins as a new antitumor treatment targeting lactate transport in cancer cells. Bioorg Med Chem. 2013 Nov 15;21(22):7107-17.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed