Description
Nimbolide is a natural inhibitor of pancreatic cancer growth and metastasis through ROS-mediated apoptosis. It inhibits epithelial-to-mesenchymal transition.
Product information
CAS Number: 25990-37-8
Molecular Weight: 466.52
Formula: C27H30O7
Chemical Name: 8(R)-(3-Furanyl)-2aR, 5aR, 6S, 6aR, 8R, 9, 9aR, 10aS, 10bR, 10cR-decahydro-2a, 5a, 6a, 7-tetramethyl-2, 5-dioxo-2H, 5H-cyclopenta[d']naphtho[1, 8-bc:2, 3-b']difuran-6-acetic acid, methyl ester
Smiles: CC1[C@@H](C[C@H]2O[C@@H]3[C@@H]4OC(=O)[C@]5(C)C=CC(=O)[C@@](C)([C@H]54)[C@@H](CC(=O)OC)[C@]3(C)C=12)C1=COC=C1
InChiKey: JZIQWNPPBKFOPT-LSYMHUITSA-N
InChi: InChI=1S/C27H30O7/c1-13-15(14-7-9-32-12-14)10-16-20(13)27(4)17(11-19(29)31-5)26(3)18(28)6-8-25(2)22(26)21(23(27)33-16)34-24(25)30/h6-9,12,15-17,21-23H,10-11H2,1-5H3/t15-,16-,17-,21-,22+,23-,25-,26+,27-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Bodduluru LN, et al. Chemopreventive and therapeutic effects of nimbolide in cancer: the underlying mechanisms. Toxicol In Vitro. 2014 Aug;28(5):1026-35.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.