Nucleoside-Analog-2

Nucleoside-Analog-2 is a 4'-Azidocytidine analogue, used to against Hepatitis C virus (HCV) replication.

Product information

CAS Number: 876708-01-9

Molecular Weight: 285.21

Formula: C9H11N5O6

Chemical Name: 1-[(2R, 3S, 4S, 5R)-5-azido-3, 4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1, 2, 3, 4-tetrahydropyrimidine-2, 4-dione

Smiles: [N-]=[N+]=N[C@]1(CO)O[C@H]([C@@H](O)[C@@H]1O)N1C=CC(=O)NC1=O

InChiKey: FHPJZSIIXUQGQE-XZMZPDFPSA-N

InChi: InChI=1S/C9H11N5O6/c10-13-12-9(3-15)6(18)5(17)7(20-9)14-2-1-4(16)11-8(14)19/h1-2,5-7,15,17-18H,3H2,(H,11,16,19)/t5-,6-,7+,9+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 20 mg/mL (70.12 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Nucleoside-Analog-2 is a 4'-Azidocytidine analogue against Hepatitis C virus (HCV) replication.

References:

1. Smith DB, et al. The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine. J Med Chem. 2009 Jan 8;52(1):219-23.

Products are for research use only. Not for human use.