GW791343 trihydrochloride


Catalog No. Size PriceQuantity
M10057-2 Solid 2 mg $95
M10057-10 Solid 10 mg $285

Description

GW791343 is a P2X7 allosteric modulator. GW791343 exhibits species-specific activity; acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7.

Product information

CAS Number: 309712-55-8

Molecular Weight: 483.81

Formula: C20H27Cl3F2N4O

Chemical Name: 2-[(3,4-difluorophenyl)amino]-N-{2-methyl-5-[(piperazin-1-yl)methyl]phenyl}acetamide trihydrochloride

Smiles: Cl.Cl.Cl.CC1=CC=C(CN2CCNCC2)C=C1NC(=O)CNC1C=C(F)C(F)=CC=1

InChiKey: WSBRAHWNJBXXJM-UHFFFAOYSA-N

InChi: InChI=1S/C20H24F2N4O.3ClH/c1-14-2-3-15(13-26-8-6-23-7-9-26)10-19(14)25-20(27)12-24-16-4-5-17(21)18(22)11-16;;;/h2-5,10-11,23-24H,6-9,12-13H2,1H3,(H,25,27);3*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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