AH10639 phosphate

AH10639 is a novel inhibitor of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase.

Product information

CAS Number: 84176-65-8

Molecular Weight: 344.31

Formula: C12H21N6O4P

Synonym:

Antimalarial agent 1

AH-10639

Antibiotic O-129

O 129

NSC-98771

Related CAS Number:

3810-29-5 (free base)

Chemical Name: 2, 4-Diamino-6, 7-diisopropylpteridine Phosphate

Smiles: CC(C)C1=NC2=C(N=C1C(C)C)N=C(N)N=C2N.OP(O)(O)=O

InChiKey: YNQBQYASRYRNRY-UHFFFAOYSA-N

InChi: InChI=1S/C12H18N6.H3O4P/c1-5(2)7-8(6(3)4)16-11-9(15-7)10(13)17-12(14)18-11;1-5(2,3)4/h5-6H,1-4H3,(H4,13,14,16,17,18);(H3,1,2,3,4)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in 10 mg/ml in water

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. MCCONNACHIE EW, et al. The action of 2:4-diamino-6:7-diisopropylpteridine on normal, proguanil- and sulphadiazine-resistant strains of Plasmodium gallinaceum. arasitology. 1953 Jan;42(3-4):272-6.

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