Niclosamide

Azeliragon free base, also known as TTP488 and PF-04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's-associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for Alzheimer's disease and cerebral amyloid angiopathy.

Product information

CAS Number: 50-65-7

Molecular Weight: 327.12

Formula: C13H8Cl2N2O4

Synonym:

Niclocide

BAY2353

Cestocid

Sagimid

Yomesan

Chemical Name: 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide

Smiles: OC1=CC=C(Cl)C=C1C(=O)NC1=CC=C(C=C1Cl)N(=O)=O

InChiKey: RJMUSRYZPJIFPJ-UHFFFAOYSA-N

InChi: InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.