Description
BAG 956, also known as NVP-BAG956, is a dual PDK1 and class I PI 3-kinase inhibitor. BAG 956 has been shown to inhibit cellular AKT phosphorylation at Thr308. BAG 956 also blocks cell proliferation and causes arrest in the G1 phase of the cell cycle. BAG 956 has been shown to slow tumor progression in mouse xenograft models.
Product information
CAS Number: 853910-02-8
Molecular Weight: 427.50
Formula: C28H21N5
Chemical Name: 2-methyl-2-(4-{2-methyl-8-[2-(pyridin-3-yl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl}phenyl)propanenitrile
Smiles: CC1=NC2=CN=C3C=CC(=CC3=C2N1C1C=CC(=CC=1)C(C)(C)C#N)C#CC1=CN=CC=C1
InChiKey: GVPAGJWVBUZHNQ-UHFFFAOYSA-N
InChi: InChI=1S/C28H21N5/c1-19-32-26-17-31-25-13-8-20(6-7-21-5-4-14-30-16-21)15-24(25)27(26)33(19)23-11-9-22(10-12-23)28(2,3)18-29/h4-5,8-17H,1-3H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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