AS-605240


Catalog No. Size PriceQuantity
M10945-2 Solid 2 mg $80
M10945-10 Solid 10 mg $240

Description

AS605240 is a selective PI3Kgamma inhibitor, has been proved effective on several inflammatory diseases. Orally administration of AS605240 significantly prevented lung inflammation and reduced collagen deposition. AS605240 also inhibited augmented expression of TNF-alpha and IL-1beta induced by bleomycin instillation. AS605240 may be a useful in treating inflammation diseases. AS605240 may represent a promising novel agent for the future therapy of pulmonary fibrosis.

Product information

CAS Number: 648450-29-7

Molecular Weight: 257.27

Formula: C12H7N3O2S

Chemical Name: (5Z)-5-[(quinoxalin-6-yl)methylidene]-1,3-thiazolidine-2,4-dione

Smiles: O=C1NC(=O)S/C/1=C\C1=CC2=NC=CN=C2C=C1

InChiKey: SQWZFLMPDUSYGV-POHAHGRESA-N

InChi: InChI=1S/C12H7N3O2S/c16-11-10(18-12(17)15-11)6-7-1-2-8-9(5-7)14-4-3-13-8/h1-6H,(H,15,16,17)/b10-6-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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