ZUN64390

ZUN64390, also known as PI3Kδ-IN-1, is a potent, selective, and efficacious PI3Kδ inhibitor with an IC50 of 1.7 nM. ZUN64390 was first reported in J Med Chem. 2017 Jun 22;60(12):5193-5208.

Product information

CAS Number: 1911564-39-0

Molecular Weight: 471.44

Formula: C22H20F3N7O2

Synonym:

PI3Kδ-IN-1

Chemical Name: 2-(4-acetyl-3, 3-dimethyl-2-oxopiperazin-1-yl)-4-(4-amino-5-(trifluoromethyl)pyrrolo[2, 1-f][1, 2, 4]triazin-7-yl)benzonitrile

Smiles: CC1(C)C(=O)N(CCN1C(C)=O)C1=CC(=CC=C1C#N)C1=CC(=C2C(N)=NC=NN12)C(F)(F)F

InChiKey: ZDXIDBRGTYDHBQ-UHFFFAOYSA-N

InChi: InChI=1S/C22H20F3N7O2/c1-12(33)31-7-6-30(20(34)21(31,2)3)16-8-13(4-5-14(16)10-26)17-9-15(22(23,24)25)18-19(27)28-11-29-32(17)18/h4-5,8-9,11H,6-7H2,1-3H3,(H2,27,28,29)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.