ZXH 3-26

ZXH-3-26 is a selective PROTAC BRD4 degrader.

Product information

CAS Number: 2243076-67-5

Molecular Weight: 821.73

Formula: C38H38Cl2N8O7S

Chemical Name: methyl 2-((6S)-4-(4-chlorophenyl)-2-((5-((2-(2, 6-dioxopiperidin-3-yl)-1, 3-dioxoisoindolin-4-yl)amino)pentyl)carbamoyl)-3, 9-dimethyl-6H-thieno[3, 2-f][1, 2, 4]triazolo[4, 3-a][1, 4]diazepin-6-yl)acetate hydrochloride

Smiles: Cl.CC1C2=C(SC=1C(=O)NCCCCCNC1=CC=CC3=C1C(=O)N(C1CCC(=O)NC1=O)C3=O)N1C(=NN=C1C)[C@H](CC(=O)OC)N=C2C1C=CC(Cl)=CC=1

InChiKey: PPIOEVXQEWNZJE-XZTCEYQHSA-N

InChi: InChI=1S/C38H37ClN8O7S.ClH/c1-19-29-31(21-10-12-22(39)13-11-21)42-25(18-28(49)54-3)33-45-44-20(2)46(33)38(29)55-32(19)35(51)41-17-6-4-5-16-40-24-9-7-8-23-30(24)37(53)47(36(23)52)26-14-15-27(48)43-34(26)50;/h7-13,25-26,40H,4-6,14-18H2,1-3H3,(H,41,51)(H,43,48,50);1H/t25-,26?;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 78.53 mg/mL(100 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.