1-(Isopropylthio)-2, 3, 4, 6-tetra-o-Ac-beta-D-glucosylpyranose


Catalog No. Size PriceQuantity
M13649-2 Contact sales@xcessbio.com for quotation $100

Description

1-(Isopropylthio)-2,3,4,6-tetra-o-Ac-beta-D-glucosylpyranose is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

Molecular Weight: 362.44

Formula: C16H26O7S

Chemical Name: [(2R,3S,4R,5R,6S)-3,4-bis(acetyloxy)-5-methyl-6-(propan-2-ylsulfanyl)oxan-2-yl]methyl acetate

Smiles: CC(C)S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1C

InChiKey: TUVSIRVFMYXHBF-VRSYBVEWSA-N

InChi: InChI=1S/C16H26O7S/c1-8(2)24-16-9(3)14(21-11(5)18)15(22-12(6)19)13(23-16)7-20-10(4)17/h8-9,13-16H,7H2,1-6H3/t9-,13-,14-,15-,16+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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