Description
C-NH-Boc-C-Bis-(C-PEG1-Boc) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1807503-91-8
Molecular Weight: 447.56
Formula: C22H41NO8
Chemical Name: tert-butyl 3-{3-[3-(tert-butoxy)-3-oxopropoxy]-2-{[(tert-butoxy)carbonyl]amino}propoxy}propanoate
Smiles: CC(C)(C)OC(=O)NC(COCCC(=O)OC(C)(C)C)COCCC(=O)OC(C)(C)C
InChiKey: AGLASZLADDHYAZ-UHFFFAOYSA-N
InChi: InChI=1S/C22H41NO8/c1-20(2,3)29-17(24)10-12-27-14-16(23-19(26)31-22(7,8)9)15-28-13-11-18(25)30-21(4,5)6/h16H,10-15H2,1-9H3,(H,23,26)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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