LG-100064


Catalog No. Size PriceQuantity
M19563-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

LG-100064 is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ; LG-100064 can be used in the research of cancer.

Product information

CAS Number: 153559-46-7

Molecular Weight: 350.45

Formula: C23H26O3

Chemical Name: 4-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acid

Smiles: CC1C=C2C(=CC=1C(=O)C1C=CC(=CC=1)C(O)=O)C(C)(C)CCC2(C)C

InChiKey: QADGBOQVBUXZKO-UHFFFAOYSA-N

InChi: InChI=1S/C23H26O3/c1-14-12-18-19(23(4,5)11-10-22(18,2)3)13-17(14)20(24)15-6-8-16(9-7-15)21(25)26/h6-9,12-13H,10-11H2,1-5H3,(H,25,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (142.67 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

LG-100064 (3-Methyl-TTNCB) is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ. LG-100064 shows no effect on RARα/β/γ (EC50, >10000 nM).

Products are for research use only. Not for human use.

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