Description
BD1063 dhydrochloride is a potent and selective sigma 1 receptor antagonist.
Product information
CAS Number: 206996-13-6
Molecular Weight: 346.12
Formula: C13H20Cl4N2
Chemical Name: 1-[2-(3,4-dichlorophenyl)ethyl]-4-methyl-piperazine, dihydrochloride
Smiles: Cl.Cl.CN1CCN(CCC2=CC(Cl)=C(Cl)C=C2)CC1
InChiKey: NXFDBTLQOARIMH-UHFFFAOYSA-N
InChi: InChI=1S/C13H18Cl2N2.2ClH/c1-16-6-8-17(9-7-16)5-4-11-2-3-12(14)13(15)10-11;;/h2-3,10H,4-9H2,1H3;2*1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 10 mg/mL(28.89 mM). Water: 69 mg/mL(199.35 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Sabino V, et al. The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking. Neuropsychopharmacology. 2009 May;34(6):1482-93. [2]. Cottone P, et al. Antagonism of sigma-1 receptors blocks compulsive-like eating. Neuropsychopharmacology. 2012 Nov;37(12):2593-604. [3]. Nieto FR, et al. Role of sigma-1 receptors in paclitaxel-induced neuropathic pain in mice. J Pain. 2012 Nov;13(11):1107-21.
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