SRT1720

SRT-1720, also known as CAY10559 and is a drug developed by Sirtris Pharmaceuticals intended as a small-molecule activator of the sirtuin subtype SIRT1. It has similar activity in the body to the known SIRT1 activator resveratrol, but is 1000x more potent. In animal studies it was found to improve insulin sensitivity and lower plasma glucose levels in fat, muscle and liver tissue, and increased mitochondrial and metabolic function. A study of SRT1720 conducted by the National Institute on Aging found that the drug may extend the lifespan of obese mice by 44% .

Product information

CAS Number: 925434-55-5

Molecular Weight: 469.56

Formula: C25H23N7OS

Synonym:

CAY-10559

SIRT-1933

Related CAS Number:

1001645-58-4 (SRT-1720 HCl)

Chemical Name: N-(2-(3-(piperazin-1-ylmethyl)imidazo[2, 1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide

Smiles: O=C(NC1=CC=CC=C1C1=CN2C(=N1)SC=C2CN1CCNCC1)C1=CN=C2C=CC=CC2=N1

InChiKey: IASPBORHOMBZMY-UHFFFAOYSA-N

InChi: InChI=1S/C25H23N7OS/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31/h1-8,13,15-16,26H,9-12,14H2,(H,29,33)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.