4-Epitetracycline hydrochloride

4-Epitetracycline hydrochloride is an epimer of the antibiotic Tetracycline. Epimers of Tetracycline form without catalysis and are considered degradation products. 4-Epitetracycline hydrochloride has decreased activity as an antibiotic or a Tet repressor effector but may have stronger toxic effects in animals.

Product information

CAS Number: 23313-80-6

Molecular Weight: 480.90

Formula: C22H25ClN2O8

Chemical Name: (4R,4aS,5aS,6S,12aS)-4-(dimethylamino)-4a,5a-dihydrogenio-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride

Smiles: Cl.C[C@]1(O)[C@H]2C[C@H]3[C@H](C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)C2C1=CC=CC=2O)N(C)C

InChiKey: XMEVHPAGJVLHIG-DXDJYCPMSA-N

InChi: InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15+,21+,22-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Granados-Chinchilla F, Arias-Andrés M, Rodríguez C. Tetracycline and 4-epitetracycline modified the in vitro catabolic activity and structure of a sediment microbial community from a tropical tilapia farm idiosyncratically. J Environ Sci Health B. 2013;48(4):291-301.

Products are for research use only. Not for human use.