Description
O4I1 is a potent Oct3/4 inducer.
Product information
CAS Number: 175135-47-4
Molecular Weight: 253.30
Formula: C16H15NO2
Chemical Name: 2-{4-[(4-methoxyphenyl)methoxy]phenyl}acetonitrile
Smiles: COC1C=CC(COC2C=CC(CC#N)=CC=2)=CC=1
InChiKey: QJEJLARVLKHYFW-UHFFFAOYSA-N
InChi: InChI=1S/C16H15NO2/c1-18-15-6-4-14(5-7-15)12-19-16-8-2-13(3-9-16)10-11-17/h2-9H,10,12H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 48 mg/mL (189.5 mM) Ethanol: 1 mg/mL (3.95 mM)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
O4I1 enhances Oct3/4 gene expression by approximately 2.5- and 4-fold at 10 μM and 20 μM, respectively, increases Oct3/4 protein levels, and promotes Oct3/4 mediated transcriptional activation.
References:
- Cheng X, et al. J Med Chem. 2015, 58(12), 4976-4983.
Products are for research use only. Not for human use.
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