Vatalanib dihydrochloride

Vatalanib, also known as PTK787, is an orally bioavailable anilinophthalazine with potential antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms.

Product information

CAS Number: 212141-51-0

Molecular Weight: 419.73

Formula: C20H17Cl3N4

Synonym:

PTK/ZK

CGP-79787D

CGP-79787

Chemical Name: N-(4-chlorophenyl)-4-[(pyridin-4-yl)methyl]phthalazin-1-amine dihydrochloride

Smiles: Cl.Cl.ClC1C=CC(=CC=1)NC1=NN=C(CC2C=CN=CC=2)C2=CC=CC=C21

InChiKey: AZUQEHCMDUSRLH-UHFFFAOYSA-N

InChi: InChI=1S/C20H15ClN4.2ClH/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;;/h1-12H,13H2,(H,23,25);2*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.