U-73122

U-73122 is a potent phospholipase C inhibitor or PI-PLC inhibitor. U-73122 is widely used as a tool to investigate the involvement of the phosphoinositide-specific phospholipase C (PLC) in signal transduction, particularly in studies attempting to characterize pathways leading to intracellular Ca2+ mobilization upon agonist challenge. U-73122 directly blocks PLC isoenzymes in vivo and in vitro.

Product information

CAS Number: 112648-68-7

Molecular Weight: 464.64

Formula: C29H40N2O3

Chemical Name: 1-(6-{[(1S,3aS,3bR,9bS,11aS)-7-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]amino}hexyl)-2,5-dihydro-1H-pyrrole-2,5-dione

Smiles: COC1=CC2CC[C@H]3[C@@H]4CC[C@H](NCCCCCCN5C(=O)C=CC5=O)[C@@]4(C)CC[C@@H]3C=2C=C1

InChiKey: LUFAORPFSVMJIW-ZRJUGLEFSA-N

InChi: InChI=1S/C29H40N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8,10,13-14,19,23-26,30H,3-7,9,11-12,15-18H2,1-2H3/t23-,24-,25+,26+,29+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.