Lexibulin dihydrochloride


Catalog No. Size PriceQuantity
M11320-2 Solid 2 mg $100
M11320-10 Solid 10 mg $300

Description

Lexibulin, also known as CYT997, is a n orally bioavailable small-molecule with tubulin-inhibiting, vascular-disrupting, and potential antineoplastic activities. Lexibulin inhibits tubulin polymerization in tumor blood vessel endothelial cells and tumor cells, blocking the formation of the mitotic spindle and leading to cell cycle arrest at the G2/M phase; this may result in disruption of the tumor vasculature and tumor blood flow, and tumor cell death.

Product information

CAS Number: 917111-49-0

Molecular Weight: 470.99

Formula: C24H31ClN6O2

Chemical Name: 3-ethyl-1-[2-methoxy-4-(5-methyl-4-{[(1S)-1-(pyridin-3-yl)butyl]amino}pyrimidin-2-yl)phenyl]urea hydrochloride

Smiles: Cl.CC1=CN=C(N=C1N[C@@H](CCC)C1=CN=CC=C1)C1=CC(OC)=C(C=C1)NC(=O)NCC

InChiKey: MXVHLVNAPPLZQV-FYZYNONXSA-N

InChi: InChI=1S/C24H30N6O2.ClH/c1-5-8-19(18-9-7-12-25-15-18)28-22-16(3)14-27-23(30-22)17-10-11-20(21(13-17)32-4)29-24(31)26-6-2;/h7,9-15,19H,5-6,8H2,1-4H3,(H2,26,29,31)(H,27,28,30);1H/t19-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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