Purvalanol B


Catalog No. Size PriceQuantity
M11323-2 Solid 2 mg $90
M11323-10 Solid 10 mg $270

Description

Purvalanol B, also known as NG 95, is a potent and selective CDK inhibitor that most potently inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively).

Product information

CAS Number: 212844-54-7

Molecular Weight: 432.90

Formula: C20H25ClN6O3

Chemical Name: 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-methylbutan-2-yl]amino}-9-(propan-2-yl)-9H-purin-6-yl)amino]benzoic acid

Smiles: CC(C)N1C=NC2C1=NC(N[C@@H](CO)C(C)C)=NC=2NC1=CC(Cl)=C(C=C1)C(O)=O

InChiKey: ZKDXRFMOHZVXSG-HNNXBMFYSA-N

InChi: InChI=1S/C20H25ClN6O3/c1-10(2)15(8-28)24-20-25-17(16-18(26-20)27(9-22-16)11(3)4)23-12-5-6-13(19(29)30)14(21)7-12/h5-7,9-11,15,28H,8H2,1-4H3,(H,29,30)(H2,23,24,25,26)/t15-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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