DL-threo-2-methylisocitrate


Catalog No. Size PriceQuantity
M11340-2 Solid 2 mg $450
M11340-10 Solid 10 mg $1,800

Description

DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1(ICL1).IC50 value:Target: The Km of purified recombinant ICL1 for threo-D(s)L(s)-isocitrate (ICA) was determined to be 188 μM using Michaelis-Menten non-linear least squares fit, with a kcat of 5.24 s-1. The Km for DL-threo-2-methylisocitrate (MICA) was approximately fourfold higher at 718 μM with a kcat of 1.25 s-1.

Product information

CAS Number: 71183-66-9

Molecular Weight: 206.15

Formula: C7H10O7

Chemical Name: (1R,2S)-1-hydroxy-1-methylpropane-1,2,3-tricarboxylic acid

Smiles: C[C@@](O)([C@H](CC(O)=O)C(O)=O)C(O)=O

InChiKey: HHKPKXCSHMJWCF-WVBDSBKLSA-N

InChi: InChI=1S/C7H10O7/c1-7(14,6(12)13)3(5(10)11)2-4(8)9/h3,14H,2H2,1H3,(H,8,9)(H,10,11)(H,12,13)/t3-,7-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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