Cevimeline (AF 102B, SNI 2011, SNK 508) is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3.
CAS Number: 1462862-74-3
Molecular Weight: 244.78
Chemical Name: bis((2R, 5'S)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2, 2'-[1, 4]oxathiolane]) hydrate dihydrochloride
Smiles: O.Cl.Cl.C[C@@H]1O[C@@]2(CN3CCC2CC3)CS1.C[C@@H]1O[C@@]2(CN3CCC2CC3)CS1 |&1:4,6,17,19|
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
- Barbe AG. Medication-Induced Xerostomia and Hyposalivation in the Elderly: Culprits, Complications, and Management. Drugs Aging. 2018 Oct;35(10):877-885.
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