NXY-059


Catalog No. Size PriceQuantity
M11381-2 Solid 2 mg $85
M11381-10 Solid 10 mg $255

Description

Disufenton sodium, also known as Cerovive, OKN007, NXY-059, is a disulfonyl derivative of phenyl-tert-butyl nitrone (PBN), with potential anti-glioma activity. Although the exact mechanism(s) of action of OKN007 are still largely unknown, this agent appears to inhibit cancer cell proliferation and migration. This agent appears to inhibit the activity of sulfatase 2 (SULF2), a highly specific endoglucosamine-6-sulfatase that is overexpressed in the extracellular matrix of cancer cells and catalyzes the removal of sulfate from the 6-O-sulfate esters of heparin.

Product information

CAS Number: 168021-79-2

Molecular Weight: 381.33

Formula: C11H13NNa2O7S2

Chemical Name: disodium 4-[(1Z)-[tert-butyl(oxido)iminiumyl]methyl]benzene-1,3-disulfonate

Smiles: [Na+].[Na+].CC(C)(C)/[N+](/[O-])=C/C1=CC=C(C=C1S([O-])(=O)=O)S([O-])(=O)=O

InChiKey: XLZOVRYBVCMCGL-BPNVQINPSA-L

InChi: InChI=1S/C11H15NO7S2.2Na/c1-11(2,3)12(13)7-8-4-5-9(20(14,15)16)6-10(8)21(17,18)19;;/h4-7H,1-3H3,(H,14,15,16)(H,17,18,19);;/q;2*+1/p-2/b12-7-;;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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