Eprodisate Sodium


Catalog No. Size PriceQuantity
M11419-2 2mg solid $80
M11419-10 10mg solid $240

Description

Eprodisate, also known as 3-PDS; NC-503; 3PDS, is an orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. Upon administration, eprodisate competitively binds to the glycosaminoglycan binding sites on serum amyloid A (SAA), which inhibits the formation of the glycosaminoglycan-amyloid fibril aggregate. This prevents the formation of amyloid deposits in certain organs, especially the kidneys, in AA amyloidosis.

Product information

CAS Number: 36589-58-9

Molecular Weight: 248.19

Formula: C3H6Na2O6S2

Synonym:

NC-503

3-PDS

3PDS

Chemical Name: 1, 3-Propanedisulfonic acid, disodium salt

Smiles: [Na+].[Na+].[O-]S(=O)(=O)CCCS([O-])(=O)=O

InChiKey: DKGJFKPIUSHDIT-UHFFFAOYSA-L

InChi: InChI=1S/C3H8O6S2.2Na/c4-10(5,6)2-1-3-11(7,8)9;;/h1-3H2,(H,4,5,6)(H,7,8,9);;/q;2*+1/p-2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Water: 49 mg/mL(197.42 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Clinicaltrials gov. Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis. May 15, 2015. Retrieved 12 June 2015.

Products are for research use only. Not for human use.

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