Catalog No. Size PriceQuantity
M11458-2 2mg solid $105
M11458-10 10mg solid $315


BUN49048, also known as CSF1R-IN-1, is a CSF1R inhibitor with an with an IC50 of 0.5 nM. BUN49048 was first reported in Bioorg Med Chem Lett. 2017 May 15;27(10):2153-2160.

Product information

CAS Number: 2095849-04-8

Molecular Weight: 479.45

Formula: C25H20F3N5O2



Chemical Name: 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide

Smiles: CC1=CC=C(C=C1NC(=O)C1=CN=CC(=C1)C1C=NN(C)C=1)NC(=O)C1=CC(=CC=C1)C(F)(F)F


InChi: InChI=1S/C25H20F3N5O2/c1-15-6-7-21(31-23(34)16-4-3-5-20(9-16)25(26,27)28)10-22(15)32-24(35)18-8-17(11-29-12-18)19-13-30-33(2)14-19/h3-14H,1-2H3,(H,31,34)(H,32,35)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 83.33 mg/mL (173.80 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Ramachandran SA, et al. Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors. Bioorg Med Chem Lett. 2017 May 15;27(10):2153-2160.

Products are for research use only. Not for human use.

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