BI-187004


Catalog No. Size PriceQuantity
M11474-2 2mg solid $150
M11474-10 10mg solid $450

Description

BI-187004, also known as VTP-34072, is an 11β-hydroxysteroid dehydrogenase 1 inhibitor. BI187004/VTP-34072 is being studied for the treatment of type 2 diabetes and metabolic syndrome. In preclinical studies, BI187004/VTP-34072 had a positive impact on multiple cardiovascular and metabolic risk factors associated with metabolic syndrome, which differentiates it from other classes of type 2 diabetes drugs.

Product information

CAS Number: 1303515-32-3

Molecular Weight: 342.39

Formula: C21H18N4O

Synonym:

VTP-34072

Chemical Name: (4aR, 9aS)-1-(1H-Benzimidazol-6-ylcarbonyl)-2, 3, 4, 4a, 9, 9a-hexahydro-1H-indeno[2, 1-b]pyridine-6-carbonitrile

Smiles: N#CC1=CC2[C@H]3CCCN([C@H]3CC=2C=C1)C(=O)C1C=C2NC=NC2=CC=1

InChiKey: VVZNCSHIBODHMZ-UZLBHIALSA-N

InChi: InChI=1S/C21H18N4O/c22-11-13-3-4-14-10-20-16(17(14)8-13)2-1-7-25(20)21(26)15-5-6-18-19(9-15)24-12-23-18/h3-6,8-9,12,16,20H,1-2,7,10H2,(H,23,24)/t16-,20+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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