Pomalidomide 4'-PEG2-azide

Catalog No. Size PriceQuantity
M11483-2 2 mg solid $105
M11483-10 10 mg solid $210
M11483-C Contact sales@xchem.com for quotation $100


Pomalidomide 4'-PEG2-azide is a cereblon ligand with PEG linker and terminal azide for onward chemistry.

Product information

CAS Number: 2271036-45-2

Molecular Weight: 430.41

Formula: C19H22N6O6

Chemical Name: 4-[[2-[2-(2-Azidoethoxy)ethoxy]ethyl]amino]-2-(2, 6-dioxo-3-piperidinyl)-1H-isoindole-1, 3(2H)-dione

Smiles: [N-]=[N+]=NCCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O


InChi: InChI=1S/C19H22N6O6/c20-24-22-7-9-31-11-10-30-8-6-21-13-3-1-2-12-16(13)19(29)25(18(12)28)14-4-5-15(26)23-17(14)27/h1-3,14,21H,4-11H2,(H,23,26,27)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.


  1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Products are for research use only. Not for human use.

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