Description
Thalidomide 4'-ether-alkylC8-amine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with a terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.
Product information
CAS Number: 2636798-38-2
Molecular Weight: 437.92
Formula: C21H28ClN3O5
Synonym:
WUN-98382
Chemical Name: 4-[(8-Aminooctyl)oxy]-2-(2, 6-dioxo-3-piperidinyl)-1H-isoindole-1, 3(2H)-dione hydrochloride
Smiles: Cl.NCCCCCCCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
InChiKey: WNWBISFFTQAOHN-UHFFFAOYSA-N
InChi: InChI=1S/C21H27N3O5.ClH/c22-12-5-3-1-2-4-6-13-29-16-9-7-8-14-18(16)21(28)24(20(14)27)15-10-11-17(25)23-19(15)26;/h7-9,15H,1-6,10-13,22H2,(H,23,25,26);1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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