(S, R, S)-AHPC-phenol-C4-NH2 dihydrochloride

Catalog No. Size PriceQuantity
M11529-2 Contact sales@xcessbio.com for quotation $100
M11529-10 Contact sales@xcessbio.com for quotation $100


(S, R, S)-AHPC-phenol-C4-NH2 dihydrochloride is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC. (S, R, S)-AHPC-phenol-C4-NH2 dihydrochloride incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand.

Product information

CAS Number: 2376990-26-8

Molecular Weight: 632.64

Formula: C28H43Cl2N5O5S


VH032-phenol-C4-NH2 dihydrochloride

Chemical Name: (2S, 4R)-N-{[2-(4-aminobutoxy)-4-(4-methyl-1, 3-thiazol-5-yl)phenyl]methyl}-1-[(2S)-2-acetamido-3, 3-dimethylbutanoyl]-4-hydroxypyrrolidine-2-carboxamide dihydrochloride

Smiles: Cl.Cl.CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1=CC=C(C=C1OCCCCN)C1SC=NC=1C)C(C)(C)C


InChi: InChI=1S/C28H41N5O5S.2ClH/c1-17-24(39-16-31-17)19-8-9-20(23(12-19)38-11-7-6-10-29)14-30-26(36)22-13-21(35)15-33(22)27(37)25(28(3,4)5)32-18(2)34;;/h8-9,12,16,21-22,25,35H,6-7,10-11,13-15,29H2,1-5H3,(H,30,36)(H,32,34);2*1H/t21-,22+,25-;;/m1../s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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