(S, R, S)-AHPC-phenol-alkylC6-amine dihydrochloride

Catalog No. Size PriceQuantity
M11532-2 2mg solid $140
M11532-10 10mg solid $420


(S, R, S)-AHPC-phenol-alkylC6-amine (dihydrochloride) is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC. (S, R, S)-AHPC-phenol-alkylC6-amine incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand.

Product information

CAS Number: 2376990-28-0

Molecular Weight: 660.70

Formula: C30H47Cl2N5O5S


VH032 phenol-alkylC6-amine dihydrochloride

Chemical Name: (2S, 4R)-N-({2-[(6-aminohexyl)oxy]-4-(4-methyl-1, 3-thiazol-5-yl)phenyl}methyl)-1-[(2S)-2-acetamido-3, 3-dimethylbutanoyl]-4-hydroxypyrrolidine-2-carboxamide dihydrochloride

Smiles: Cl.Cl.CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC1=CC=C(C=C1OCCCCCCN)C1SC=NC=1C)C(C)(C)C


InChi: InChI=1S/C30H45N5O5S.2ClH/c1-19-26(41-18-33-19)21-10-11-22(25(14-21)40-13-9-7-6-8-12-31)16-32-28(38)24-15-23(37)17-35(24)29(39)27(30(3,4)5)34-20(2)36;;/h10-11,14,18,23-24,27,37H,6-9,12-13,15-17,31H2,1-5H3,(H,32,38)(H,34,36);2*1H/t23-,24+,27-;;/m1../s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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