Description
β-Naphthoflavone-CH2-Br (β-NF-CH2-Br) is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br can be used to synthesize the PROTAC β-NF-JQ1(HY-130256).
Product information
CAS Number: 1282513-77-2
Molecular Weight: 365.22
Formula: C20H13BrO2
Synonym:
β-NF-CH2-Br
Chemical Name: 3-[4-(bromomethyl)phenyl]-1H-benzo[f]chromen-1-one
Smiles: O=C1C=C(OC2=CC=C3C=CC=CC3=C21)C1C=CC(CBr)=CC=1
InChiKey: JKXPXUCDLPRQNA-UHFFFAOYSA-N
InChi: InChI=1S/C20H13BrO2/c21-12-13-5-7-15(8-6-13)19-11-17(22)20-16-4-2-1-3-14(16)9-10-18(20)23-19/h1-11H,12H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Ohoka N, et al. Development of Small Molecule Chimeras That Recruit AhR E3 Ligase to Target Proteins. ACS Chem Biol. 2019 Oct 16.
Products are for research use only. Not for human use.
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