Thalidomide 5-fluoride

Catalog No. Size PriceQuantity
M11562-2 2mg solid $80
M11562-10 10mg solid $240


Thalidomide 5-fluoride is Thalidomide-based cereblon ligand that incorporates to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.

Product information

CAS Number: 835616-61-0

Molecular Weight: 276.22

Formula: C13H9FN2O4

Chemical Name: 2-(2, 6-dioxopiperidin-3-yl)-5-fluoro-2, 3-dihydro-1H-isoindole-1, 3-dione

Smiles: O=C1CCC(C(=O)N1)N1C(=O)C2=CC(F)=CC=C2C1=O


InChi: InChI=1S/C13H9FN2O4/c14-6-1-2-7-8(5-6)13(20)16(12(7)19)9-3-4-10(17)15-11(9)18/h1-2,5,9H,3-4H2,(H,15,17,18)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 83.33 mg/mL (301.68 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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