Catalog No. Size PriceQuantity
M11584-2 contact sales@xcessbio.com $7,000
M11584-10 contact sales@xcessbio.com $7,000


AP1867-3-(aminoethoxy), the AP1867 based moiety, is a synthetic ligand for FKBP. AP1867-3-(aminoethoxy) can be used in the synthesis of PROTAC FKBP12 F36V degrader.

Product information

CAS Number: 2127390-15-0

Molecular Weight: 678.81

Formula: C38H50N2O9

Chemical Name: (1R)-1-[3-(2-aminoethoxy)phenyl]-3-(3, 4-dimethoxyphenyl)propyl (2S)-1-[(2S)-2-(3, 4, 5-trimethoxyphenyl)butanoyl]piperidine-2-carboxylate

Smiles: CC[C@@H](C1=CC(OC)=C(OC)C(=C1)OC)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCC1C=C(OC)C(=CC=1)OC)C1=CC(=CC=C1)OCCN


InChi: InChI=1S/C38H50N2O9/c1-7-29(27-23-34(45-4)36(47-6)35(24-27)46-5)37(41)40-19-9-8-13-30(40)38(42)49-31(26-11-10-12-28(22-26)48-20-18-39)16-14-25-15-17-32(43-2)33(21-25)44-3/h10-12,15,17,21-24,29-31H,7-9,13-14,16,18-20,39H2,1-6H3/t29-,30-,31+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578.

Products are for research use only. Not for human use.

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