Imatinib carbaldehyde

Catalog No. Size PriceQuantity
M11587-2 contact $7,000
M11587-10 contact $7,000


Imatinib carbaldehyde (CGP-57148B carbaldehyde), the Imatinib (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER.

Product information

CAS Number: 1436868-85-7

Molecular Weight: 507.59

Formula: C29H29N7O2


CGP-57148B carbaldehyde

STI571 carbaldehyde

PROTAC ABL binding moiety 1

Chemical Name: 4-[(4-formylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide

Smiles: CC1=CC=C(C=C1NC1N=C(C=CN=1)C1=CC=CN=C1)NC(=O)C1C=CC(CN2CCN(CC2)C=O)=CC=1


InChi: InChI=1S/C29H29N7O2/c1-21-4-9-25(17-27(21)34-29-31-12-10-26(33-29)24-3-2-11-30-18-24)32-28(38)23-7-5-22(6-8-23)19-35-13-15-36(20-37)16-14-35/h2-12,17-18,20H,13-16,19H2,1H3,(H,32,38)(H,31,33,34)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Products are for research use only. Not for human use.

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