Catalog No. Size PriceQuantity
M11590-2 contact sales@xcessbio.com $7,000
M11590-10 contact sales@xcessbio.com $7,000


HG-7-85-01-Decyclopropane, the HG-7-85-01 (ABL inhibitor) based moiety, binds to IAP ligand via a linker to form SNIPER .

Product information

CAS Number: 2444044-44-2

Molecular Weight: 568.61

Formula: C28H27F3N6O2S


PROTAC ABL binding moiety 3

Chemical Name: N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-{2-formamido-[1, 3]thiazolo[5, 4-b]pyridin-5-yl}benzamide

Smiles: CCN1CCN(CC2=CC=C(C=C2C(F)(F)F)NC(=O)C2C=CC=C(C=2)C2=CC=C3N=C(NC=O)SC3=N2)CC1


InChi: InChI=1S/C28H27F3N6O2S/c1-2-36-10-12-37(13-11-36)16-20-6-7-21(15-22(20)28(29,30)31)33-25(39)19-5-3-4-18(14-19)23-8-9-24-26(34-23)40-27(35-24)32-17-38/h3-9,14-15,17H,2,10-13,16H2,1H3,(H,33,39)(H,32,35,38)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Products are for research use only. Not for human use.

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